Same goal, different formula—Botox and Xeomin explained

When patients ask about Botox vs. Xeomin, the answer is always the same: both are excellent neuromodulators, and the best choice depends on your individual goals. Botox and Xeomin work by relaxing targeted facial muscles to reduce the appearance of fine lines and wrinkles, especially in areas like the forehead, frown lines, and crow’s feet. Treatments are quick, minimally invasive, and designed to give you a refreshed—not frozen—look.

The main difference between Botox and Xeomin is in their formulation. Botox contains accessory proteins, while Xeomin is a purified form of botulinum toxin without those added proteins. Because Xeomin is considered a “naked” neurotoxin, it may be a great option for patients who have been using neuromodulators long-term or are concerned about developing resistance over time.

As an Aesthetic Nurse Practitioner, my priority is delivering safe, natural-looking results tailored to your facial anatomy. Botox is known for its consistency and long-standing success, while Xeomin is often chosen for its clean formulation and beautifully subtle results. During your consultation, we’ll decide together which option aligns best with your skin, lifestyle, and aesthetic goals.